MOVEMENT DISORDERS & PARKINSON'S DISEASE

Aksel Siva (Istanbul University Cerrahpasa School of Medicine, Istanbul, Turkey), a valued member of our European editorial board, talks to us about the topic of the interactive session he participated in focusing on treatment strategies in progressive multiple sclerosis. Questions 1. What criteria should guide a clinician’s decision as to when to initiate and/or escalate disease-modifying treatment in progressive multiple sclerosis (MS)? (0:04) 2. What is the current status of research into predictors in progressive MS? (1:40) Speaker disclosure: Aksel Siva has received honoraria for educational presentations and consultation fees from Novartis, Sanofi-Genzyme, F. Hoffmann-La Roche, Biogen Idec/Gen Pharma of Turkey, Merck Serono and Teva; received travel and registration coverage for attending several national or international congresses or symposia from Merck Serono, Biogen Idec/Gen Pharma of Turkey, Genzyme and , F. Hoffmann-La Roche. Filmed at the 5th Congress of the European Academy of Neurology (EAN), Oslo, Norway, June 2019.

This video is brought to you by the Stanford Medicine 25 to teach you the exam to diagnose Parkinson's Disease confidently as well as monitor response to treatment or progression of disease. The video is lead by Dr. Kathleen Poston. She is faculty at Stanford and a neurologist with an expertise in movement disorders. She is an active researcher in the field of Parkinson's Disease and an wonderful clinician. (The patient is this video, Larry, is a patient of Dr. Poston's.) * All exams are demonstrated with examples of real abnormalities thanks to our amazing patients! Special thank you to Larry for being the primary patient in this video. Larry is an amazing teacher and person! The four cardinal parts of the exam for Parkinson's Disease (covered in detail in this video) are: 1) Bradykinesia (required for diagnosis of 2) Rigidity 3) Tremor (usually rest tremor but also kinetic and intentional tremor) 4) Issues with gait and postural instability The Stanford Medicine 25 program for bedside medicine at the Stanford School of Medicine aims to promote the culture of bedside medicine to make current and future clinicians and other healthcare provides better at the art of physical diagnosis and more confident at the bedside of their patients. Visit us: Website: http://stanfordmedicine25.stanford.edu/ Blog: http://stanfordmedicine25.stanford.ed... Facebook: https://www.facebook.com/StanfordMedi... Twitter: https://twitter.com/StanfordMed25

In this video, episode 4 of the series, we discuss how pathology and symptoms progress as Parkinson's disease develops. This unique series is designed to educate newly diagnosed patients and the general public about Parkinson's disease. Dr. Rajeev Kumar is a movement disorders specialist and medical director of the Movement Disorder Center of the Colorado Neurological Institute. Images courtesy of: Free Digital Photos (www.freedigitalphotos.net)
 Stock.XCHNG (www.sxc.hu)
 Wikimedia Commons (www.commons.wikimedia.org) Series produced by Sara Rabin

We will discuss the fascinating interplay between the host immune system and viruses in triggering demyelinating diseases of the brain. Renaud Du Pasquier, M.D. is associate professor in Neurology at UNIL--CHUV. After medical studies and board certification in Internal Medicine and Neurology in Geneva, he performed a post-doc in neuroimmunology/neurovirology at the Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, from 1999 to 2004. Primarily devoted to the research in demyelinating diseases of the central nervous system, his laboratory tries to understand the respective contribution of the immune system, on one hand, and viruses, on the other hand, to the pathogenesis of multiple sclerosis and progressive multifocal leukoencephalopathy. He also holds a clinical research program dealing with the neurocognitive disorders in HIV+ patients. About TEDx: In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)

Learn with Dr.Gretchen Hawley -Physical therapist and MS specialist as she shares facts and updates on physical therapy, aspects of movement, strength, recovery, maintenance and gaining back function through neurological reserve and neuroplasticity. **Please share with others affected by MS or your family and friends!** Remember to SUBSCRIBE to MS Views and News :) Stay informed with MS news and videos. Click: http://www.register.msviewsandnews.org (takes less than 30 seconds to complete) ------------------------------------------------------------ Click here: http//www.youtube.com/msviewsandnews to watch our other Multiple Sclerosis (#MS) videos ------------------------------------------------------------ Website: http://www.msvn.org ------------------------------------------------------------ Blog (MS News archives): http://wwwmsviewsandrelatednews.blogspot.com/ ------------------------------------------------------------ Join the ms community on Social Media Pages: Facebook: http://www.facebook.com/msviewsandnews Instagram: http://www.instagram.com/msviewsandnews Twitter: http://www.twitter.com/msviews_andnews ------------------------------------------------------------ Send comments to: info@msviewsandnews.org ~~~~~~~~~~~~~~~~~~~~~~~~ Please help our mission to educate those affected by MS. Click to donate: http://www.donations.msviewsandnews.org ~~~~~~~~~~~~~~~~~~~~~~~~~

One of our newest US Neurology Editorial Board members, Rebecca Gilbert, Vice President of the American Parkinson Disease Association (APDA), kindly met with us to share her insights on the latest developments and most important advances in the treatment of Parkinson's disease. Questions 1. What are the current unmet needs in the treatment of Parkinson’s disease (PD)? (0:04) 2. What have been the most important recent developments in the treatment of motor fluctuations in patients with PD? (1:12) 3. What is your opinion on the use of deep brain stimulation in PD? (3:07) 4. What have been the most important advances in the development of disease modifying treatments in PD? (4:21) 5. What other promising clinical PD treatments are in the pipeline? (5:06) 6. What are your highlights of the AAN conference this year? (7:09) Speaker disclosure: Rebecca Gilbert has nothing to disclose in relation to this video interview. Filmed at the American Academy of Neurology (AAN) Annual Meeting, Philadelphia, USA, May 2019.

To learn more, visit https://neuropathyalliancetx.org. Texas Neuropathy Alliance of Texas is a non-profit providing education and resources to neuropathy patients, caregivers and medical providers.

Watch Me Analyze An MRI Live! Source of the MRI from Radiopaedia: https://radiopaedia.org/cases/multiple-sclerosis-45?lang=us Comment or ask questions below! I would be happy to answer! Subscribe on YouTube for more videos every Wednesday! Make video requests in the comments section! My book "Resilience in the Face of Multiple Sclerosis" on Amazon: https://www.amazon.com/dp/B07WP7H5LK Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research. Follow me on twitter: https://twitter.com/Brandon_Beaber Music: INNER GRACE - Copyright 2018 Wilton Vought Source: Really Really Free Music Link: https://youtu.be/wy9FL1-jup4 The video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.