SNAP (Study of Aging among Persons Living with HIV)
May 1, 2029
Region:
Project Status:
Ongoing
July 1, 2022
Start Date:
End Date:
Africa
Country:
Zambia
Language:
Nyanja
Category:
Global Neurology, Neuroimaging, Brain Injury, HIV
Primary Contact(s):
Gretchen Birbeck
Contact Info:
Project Needs:
Increase outreach of project/program
Funding Source:
Government
,
US NIH NINDS
Leading Institution:
University Teaching Hospitals Neurology Research Organization and Centre for Infectious Diseases Research in Zambia and Chikankata Hospital and Monze Mission Hospital and Chilenji Clinic
Associated Publications:
Description:
To conduct a prospective, exposure-control cohort study of older adults living with HIV comparing the neurological status of those who have had HIV infection for a longer period of time (long HIV group) to age, gender, and community-matched comparison group who have had HIV infection for a shorter period of time (short HIV group). In the SNAP Study, we will utilize our existing consortia of neuro-HIV rural study sites to enroll 150 HIV+ adults >45 years of age stable on ARVs for at least 10 years and an age, gender, and community-matched comparison group of HIV+ adults stable on ARVs for 1-2 years. These individuals will undergo comprehensive annual assessments and brain MRIs for 7 years to evaluate their general and neurological health and the aging process that evolves during the 7 years of assessments